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Изучение зубов акул поможет понять, возможна ли регенерация зубов у человека


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Изучение зубов акул поможет понять, возможна ли регенерация зубов у человека

Для того, чтобы выяснить, возможно ли выращивать новые человеческие зубы, группа ученых из Университета Шеффилда (University of Sheffield) тщательно изучила процесс регенерации зубов у акул.

Гарет Фрейзер (Gareth Fraser) и его коллеги обнаружили ряд генов, вовлеченный в процесс регенерации зубной ткани у акул. Они отмечают, что о регуляции этого процесса на генном уровне ранее было известно недостаточно.

Японские ученые из Центра биологии развития RIKEN (RIKEN Center for Developmental Biology) нашли способ вырастить недостающие зубы. Авторы во главе с Такаши Цухи (Takashi Tsuji) считают, что разработанный ими метод позволит решить проблему нехватки зубов, избежав использования имплантатов и мостов.

Гены экспрессировались в эпителиальных клетках, дающих начало зубным пластинкам. Эти клетки присутствуют и у человека – именно благодаря им формируются сначала молочные, а потом коренные зубы.

Несмотря на то, что обнаруженные гены ответственны за формирование зубов у всех позвоночных, их способность стимулировать регенерацию зубной ткани у человека со временем сильно снизилась.

Авторы надеются продолжить изучение экспрессии этих генов в процессе эмбриогенеза акул. Они считают, что им удастся понять, как контролируется этот процесс, что в дальнейшем пригодится для разработки терапии восстановления недостающих зубов у людей.

Источник: medportal.ru

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